Mitochondria and the Central Nervous System

Mitochondrial dysfunction is emerging as a central theme in all the major neurodegenerative diseases, while also playing key roles in ischaemic injury following stroke. In this symposium we will bring together key elements and highlight recent developments in this rapidly growing area. Our guest speakers are world leaders in their fields. Thomas Langer will talk about mitochondrial quality control, an area that has really only been understood in the last few years but which seems pivotal in defining mitochondrial - and therefore cell - health. Massimo Zeviani will talk about recent identification of novel proteins that play central roles in aspects of human mitochondrial and neurological disease. Both are outstanding scientists and superb speakers. We will also highlight the breadth of work in the field, from modelling studies in the mammalian CNS to the development of novel models in the fruit fly.
+ show speakers and program
Preliminary Schedule
9:30 Registration and coffee

10:00 - 11:00 Opening Keynote: Thomas Langer, Institute, of Genetics, Cologne
Mitochondrial quality control and disease of the CNS

11:00 - 11:30 David Attwell, University College of London
Energy Supply in the Brain

11:30 - 12:00 Coffee Break

12:00 - 12:30 Helene Plun Favreau, University College of London
Mitochondrial proteins and mitochondrial dysfunction in Parkinson's Disease

12:30 - 13:00 Kenneth Smith, University College of London
Mitochondrial dysfunction in demyelinating disease

13:00 - 14:00 Lunch Break
14:00 - 14: 30 Alex Whitworth, University of Sheffield
Modelling neurodegenerative diseases 'in drosphila'

14:30 - 15:00 Paul Chapple (Barts), William Harvey Research Institute
Sacsin and cerebellar ataxia

15:00 - 15:30 Selected talk from Abstracts

15:30 - 16:00 Afternoon Tea

16:00 - 16:30 Selected talk from Abstracts

16:30 - 17:30 Closing Keynote: Massimo Zeviani
Incoming director of the Medical Research Council of Mitochondrial Biology Unit, Cambridge, UK
Mitochondrial genetic disease and the CNS

17:30 - 19:00 Poster Reception

17 Dec - 17 Dec 2012

United Kingdom
meeting website