Yeast Genetics & Genomics

The Yeast Genetics & Genomics course is a modern, state of the art laboratory course designed to teach the students the full repertoire of genetic approaches needed to dissect complex problems in the yeast Saccharomyces cerevisiae. Combinations of classical genetic approaches are emphasized, including the isolation and characterization of mutants, tetrad analysis, complementation, and mitotic recombination. Molecular genetic techniques, including various types of yeast transformation, gene replacement with plasmids and PCR, construction and analysis of gene fusions, and generation of mutations in cloned genes, will also be emphasized. Students will use classical and molecular approaches to gain experience in identifying and interpreting various kinds of genetic interactions including suppression and synthetic lethality. Students will be immersed in yeast genomics and will perform and interpret experiments with DNA arrays. Students will gain first-hand experience in modern cytological approaches such as epitope tagging and imaging yeast cells using indirect immunofluorescence, GFP-protein fusions and a variety of fluorescent indicators for various subcellular organelles. Lectures on fundamental aspects of yeast genetics will be presented along with seminars given by outside speakers on topics of current interest.
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Last year's speakers included:
David Botstein, Princeton University
Dan Burke, University of Virginia
Maria Costanzo, Stanford University School of Medicine
Beverly Errede, University of North Carolina Chapel Hill
Marc Gartenberg, RobertWood Johnson Medical School
Daniel Gottschling, FHCRC
John Hartman IV, University of Alabama at Birmingham
Mark Johnston, University of Colorado-Denver
Jasper Rine, University of California, Berkeley
Rodney Rothstein, Columbia University Medical Center
Eric Weiss, Northwestern University
Reed Wickner, National Institutes of Health

24 Jul - 13 Aug 2013
Cold Spring Harbor
United States of America
meeting website