The Science of Malaria Eradication

Steering Committee of MESA: Pedro Alonso, Barcelona Institute for Global Health, Fred Binka, University of Ghana, Graham Brown, University of Melbourne, Chetan Chitnis, International Centre for Genetic Engineering and Biotechnology, Erin Shutes/Jessica Milman, Bill & Melinda Gates Foundation, Rob Newman, World Health Organization, Jetsumon Prachumsri, University of Mahidol, David Schellenberg, London School of Hygiene and Tropical Medicine, Marcel Tanner, Swiss Tropical Institute Meeting Summary: This Keystone Symposium provides the most comprehensive look at the cutting edge of the science of malaria eradication as it advances. For the first time since the paradigm shift from malaria control to the interruption of transmission, research, development, innovation and lessons learned will all be captured. The central goal of the meeting is to provide a unique and needed space for malaria eradication scientists to share new information and advance the scientific debate. As the field develops and results emerge, so too will the questions which need to be answered. The meeting facilities crossfertilisation between disciplines, which all have a role in advancing the science of malaria eradication. Further, in an environment conducive to creative thinking, an anticipated outcome of the meeting is the generation of ideas and the next priorities for the scientific community to tackle. Other disease eradication efforts, past and present, have taught us the critical role of research and development. The publication of the malaria eradication research agenda (malERA) in 2011 laid the foundation for this R&D effort. This meeting would serve as a significant milestone in the continual development of this research agenda. By showcasing new evidence, emerging data and new challenges the meeting aims to catalyze ideas across multiple disciplines and catalyze research activities in the field.
+ show speakers and program
Dyann F. Wirth, Harvard School of Public Health, USA
The Parasite Population in Control, Elimination and Eradication

Fabrizio Tediosi, Swiss Tropical and Public Health Institute, Switzerland
Eradication: The Economic Case

Frank O. Richards, Carter Center, USA
Pragmatic Approaches: Where to Start with Elimination

Jetsumon Prachumsri, Mahidol University, Thailand
Inhibition of Parasite Development in Different Vectors

Anthony A. James, University of California, Irvine, USA
Genetic Manipulation of Mosquitos

Marcelo Jacobs-Lorena, Johns Hopkins Bloomberg School of Public Health, USA
Fighting Malaria with Engineered Symbiotic Bacteria from Vector Mosquitoes

Elizabeth Ann Winzeler, University of California San Diego, School of Medicine, USA
Genetic Approaches to Identify New Targets

Timothy N.C. Wells, Medicines for Malaria Venture (MMV), Switzerland
Drug Discovery for Malaria Eradication, Liver Stages and Gametocyticidal Agents

Marcus G. Lacerda, Tropical Medicine Foundation of Amazonas, Brazil
Drugs for Plasmodium vivax

David Smith, Johns Hopkins Bloomberg School of Public Health, USA
How Stable is Elimination?

Thomas A. Smith, Swiss Tropical and Public Health Institute, Switzerland
Modeling Intervention Mixes

David Kaslow, PATH, USA
Profiling Immune Responses to Inform Vaccine Development

Patrick E. Duffy, National Institute of Allergy and Infectious Diseases, USA
Targeting Transmission Stages

Stephen L. Hoffman, Sanaria, USA
Whole Cell Organisms

Richard W. Steketee, PATH, USA
Measuring Transmission

Ivo Mueller, Barcelona Centre for International Health Research (CRESIB) and the Walter & Eliza Hall Institute, Spain
Transmission of Plasmodium viviax

Sarah K. Volkman, Harvard School of Public Health, USA
Using Genomics To Understand Malaria Transmission Toward Elimination and Eradication

Robert E. Sinden, Imperial College London, UK
Identifying Biological Challenges: Trojan Horses of the Parasite Life-Cycle

Hernando Del Portillo Obando, Barcelona Centre for International Health Research (CRESIB), Spain
Reticulocyte-Derived Exosomes: An Intercellular Communicator in Plasmodium vivax Malaria?

Oliver Billker, Wellcome Trust Sanger Institute, UK
Signaling Pathways for Development of Transmission Stages

David Bell, Foundation for Innovative New Diagnostics (FIND), Switzerland
Diagnostic Priorities: Sustaining Gains When Parasites and Funders are Waning

Justin M. Cohen, Clinton Health Access Initiative (CHAI), USA
Surveillance Strategies to Guide Elimination Operations

Marcel Tanner, Swiss Tropical and Public Health Institute, Switzerland
Surveillance and Response: The Challenges for Science and Elimination Actions

Closing Keynote Address
Peter C. Agre, Johns Hopkins Malaria Research Institute, USA
Opening Doors Worldwide Through Medical Science

2 Feb - 7 Feb 2014
meeting website