Molecular Cell Biology of Macrophages in Human Diseases

In recent years, studies of the development, genetics, and molecular cell biology of macrophages has advanced our understanding of their major role in health and diseases. Many questions remain to be answered with respect to mechanisms that control macrophage development and function, particularly in the context of human genetic heterogeneity. Recent discoveries have also revealed greater heterogeneity in macrophage function and origins than previously appreciated. Answering these questions will have major implications for human health and disease. To help meet this challenge, this meeting will bring together leading and upcoming scientists in immunology, infectious diseases, metabolism, molecular biology and genetics, development, cancer, and cell migration with a common interest in macrophages and their roles in human diseases. In addition to the regular sessions, three “macrophage leading edge” workshops will provide a platform to discuss the findings of young scientists, selected from the submitted abstracts to present their work. These workshops will additionally help to focus the meeting on some of the fastest moving areas of macrophage biology.
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Keynote Address
Carl F. Nathan, Weill Cornell Medical College, USA

Christopher K. Glass, University of California, San Diego, USA
Genomics and Lipidomics of Macrophage Activation

Gioacchino Natoli, IEO, European Institute of Oncology, Italy
Epigenomic Control of Macrophage Gene Expression

Ellen V. Rothenberg, California Institute of Technology, USA
Lessons from Genomic Analysis of T Cell Development

Frederic Geissmann, King's College London, UK
Developmental Heterogeneity of Macrophages

David Traver, University of California, San Diego, USA
Development of Myeloid Cells

Michael H. Sieweke, Centre d'Immunologic Marseille-Luming, France
Control of Macrophage Proliferation

Aldons J. Lusis, University of California, Los Angeles, USA
Leveraging the Power of Natural Genetic Variation to Understand Macrophage Biology

Philippe Gros, McGill University, Canada
IRFs, Macrophages and Infectious Diseases

Shigekazu Nagata, Kyoto University, Japan
Eat-Me Signals

Philippe Herbomel, Institut Pasteur, France
Development of Tissue Resident Macrophages Populations in Zebrafish

Judith E. Allen, University of Edinburgh, UK
Macrophage Activation in Th2 Immunity

Ellen A. Robey, University of California, Berkeley, USA
Lymph Node Macrophages

Adriano M. Aguzzi, University Hospital of Zurich, Switzerland
Follicular Dendritic Cells and Chronic Inflammation

Fiona Pixley, University of Western Australia, Australia
CSF-1 Receptor Signaling and Macrophage Motility

Wolfgang Weninger, Centenary Institute, Australia
Perivascular Macrophages as Regulators of Neutrophil Recruitment to the Skin

Valerie O'Donnell, Cardiff University, UK
Lipid Mediators

Ira Mellman, Genentech, Inc., USA

Steffen Jung, Weizmann Institute of Science, Israel
Gut Macrophages and DCs

Mikael J. Pittet, Massachusetts General Hospital, USA
Monocyte/Macrophages in Cancer

Fabio Rossi, University of British Columbia, Canada
Microglia and CNS Inflammation

Ajay Chawla, University of California, San Francisco, USA
Macrophages and Obesity

Leonie S. Taams, King's College London, UK
Regulating Inflammation: Studying the Cross-Talk between Monocytes/Macrophages and CD4+ T Cells in Rheumatoid Arthritis

Kathryn J. Moore, New York University Medical Center, USA
Macrophage Retention in Metabolic Diseases

Catherine (Lynn) Hedrick, La Jolla Institute for Allergy and Immunology, USA
Monocytes in Atherosclerosis

Anthony W. Segal, University College London, UK
The Role of Macrophages in the Causation of Crohn’s Disease

Kinya Otsu, King's College London, UK
Mitochondrial DNA in the Development of Inflammation and Heart Failure

Ruslan M. Medzhitov, HHMI, Yale University School of Medicine, USA
Macrophages: A Distributed Control System for Homeostasis and Inflammation

9 Feb - 14 Feb 2014
Santa Fe
United States of America
meeting website