Alzheimer's Disease in Down Syndrome: From molecules to cognition

This new Wellcome Trust conference will focus on understanding the links between Down syndrome and Alzheimer's disease. With the Down syndrome population now approaching eight million, it is important to understand the nature and cause of the AD-like dementia that can occur in this disease. Our aim is to understand dementia in Down syndrome at the neurological, cognitive, behavioural, cellular and genetic levels, which will also inform our general understanding of Alzheimer's disease.

This multi-disciplinary meeting will focus on the development of biomarkers for early diagnosis of dementia in Down syndrome, the biochemical and cellular characteristics that differentiate those who will develop dementia from those who are protected, the genetics of behavioural and cognitive phenotypes seen in Alzheimer's disease and Down syndrome, and stem cell approaches to therapies for dementia. Panel discussions will be arranged on aspects of clinical studies in Alzheimer's disease and Down syndrome.

The meeting is aimed at clinicians, geneticists, neuroscientists and psychologists with an interest in Down syndrome and/or Alzheimer's disease. We welcome abstracts from all areas relevant to furthering our understanding of dementia in these diseases. Several oral presentations will be chosen from the abstracts submitted.
+ show speakers and program
Scientific organising committee
Elizabeth Fisher University College London, UK
John Hardy University College London, UK
Annette Karmiloff-Smith Birkbeck, University of London, UK
Dean Nizetic Queen Mary, University of London, UK
Andre Strydom University College London, UK
Victor Tybulewicz National Institute for Medical Research, UK
Frances Wiseman University College London, UK

Keynote speaker
Bill Mobley University of California San Diego, USA

Jorge Busciglio University of California San Diego, USA
Noel Buckley King's College London, UK
Antonia Coppus Radboud University Medical Centre, The Netherlands
Jamie Edgin University of Arizona, USA
John Hardy University College London, UK
Eric Karran Alzheimer's Research UK, UK
Omar Khwaja F. Hoffmann-La Roche AG, Switzerland
Jeanne Lawrence University of Massachusetts Medical School, USA
Joseph Lee Columbia University, USA
Rick Livesey University of Cambridge, UK
Carolyn Mervis University of Louisville, USA
Ralph Nixon NYU Langone Medical Center, USA
Dean Nizetic Queen Mary, University of London, UK
Jorge Palop University of California San Francisco, USA
Amy Pooler King's College London, UK
Jee Hoon Roh Asan Medical Center, South Korea
Nicole Schupf Columbia University Medical Center, USA
Frances Wiseman University College London, UK
Additional speakers will added shortly

27 Mar - 29 Mar 2014
United Kingdom
meeting website