This course emphasizes genetic applications and approaches to drug addiction research through methodological instruction based on literature, data sets and informatics resources drawn from studies of addiction related phenotypes. The course includes plenary sessions on major progress in addiction genetics, and discussion sessions in which students present their work for discussion on applications of genetic methods. Students will leave the course able to design and interpret genetic and genomic studies of addiction as they relate to their specific research question, and will be able to make use of current bioinformatics resources to identify research resources and make use of public data sources in their own research.
+ show speakers and program
The 2014 event schedule is being developed and will be posted as soon as possible. In the meantime, please view the 2013 event schedule for an idea of course content and structure.
Saturday, August 17th
5:00 PM Registration and Reception at Highseas
6:00-8:00 Dinner and introductions
Sunday, August 18th Overview of psychology, biology and genetics of addiction
7:30-8:45AM Breakfast
8:45-9:00 Course Overview
Elissa Chesler, Ph.D., The Jackson Laboratory and
Abraham Palmer, Ph.D., University of Chicago
9:00-10:30 Overview of Alcoholism and Addiction
Wade Berrettini, M.D., Ph.D., University of Pennsylvania
10:30-10:45 Break
10:45-12:15 Overview of Alcoholism and Addiction Genetics
James MacKillop, Ph.D., University of Georgia
12:15-1:15PM Lunch
1:15—2:15 Mouse models of addiction-delay discounting
Nicholas Grahame, Ph.D., Indiana University-Purdue University, Indianapolis
2:15-3:15 Reinforcement Learning
Paul John Kenny, Ph.D., The Scripps Research Institute- Florida
3:15-3:30 Break
3:30-4:30 Human Intermediate Phenotypes Related to Drug Abuse
Harriet de Wit, Ph.D., University of Chicago
4:30-5:30 Multi-dimensionality and comorbidity of addiction
Victor Hesselbrock, Ph.D., University of Connecticut Health Center
5:30-6:00 Discussion and Q & A Panel
6:00-6:15 Cocktails
6:15-7:30 Dinner
7:30-9:30 Evening Discussion: Student White Boards (5 minutes per student)
Monday, August 19th Genetic and genomic analysis in addiction
7:30-9:00AM Breakfast
9:00-10:00 Making and Using Mutant Mice
Lisa Tarantino, Ph.D., University of North Carolina
10:00-11:00 MicroRNA/Molecular Mechanisms of Addiction
Paul John Kenny, Ph.D., The Scripps Research Institute- Florida
11:00-11:15 Break
11:15-12:15 Genetic Mapping Populations
Abraham Palmer, Ph.D., University of Chicago
12:15-1:15PM Lunch
1:15-2:15 Using Simple experimental crossing in mice to study complex traits
Gary Churchill, Ph.D., The Jackson Laboratory
2:15-3:15 Gene Expression Analysis and eQTL
Shannon McWeeney, Ph.D., Oregon Health & Science University
3:15-3:30 Break
3:30-4:30 Overview Techniques in Human Genetics Analysis
Richard Crist, Ph.D., University of Pennsylvania
4:30-5:30 Nicotine GWAS – Anatomy of a Success Story
Thorgeir E. Thorgeirsson, Ph.D., deCODE Genetics
5:30-6:00 Discussion
6:00-6:15 Cocktails
6:15-7:30 Dinner
7:30 Free Evening
Tuesday, August 20th Bioinformatics and systems biology in the genetics of
addiction
7:30-9:00AM Breakfast
9:00-9:15 Introduction/overview to the bioinformatics of behavior
Elissa Chesler, Ph.D., The Jackson Laboratory
9:15-10:00 Human Genetics: Hapmap, 1000 Genomes, PLINK, dbGAP, NHLBI
Richard Crist, Ph.D., University of Pennsylvania
10:00-10:45 The data landscape of genetics of addiction, a perspective from NIF
Anita Bandrowski, Ph.D., University of California, San Diego
10:45-11:15 Systems Genetics and Integrative Genomics
Elissa Chesler, Ph.D., The Jackson Laboratory
11:15-11:45 Mouse Genome Informatics and The Center for Genome Dynamics
Susan McClatchy, The Jackson Laboratory
11:45-12:15 Mouse Phenome Database
Molly Bogue, The Jackson Laboratory
12:15-12:45 Gene Expression Analysis
Shannon McWeeney, Ph.D., OHSU Knight Cancer Institute Rev. 8/12/13
12:45-1:45PM Lunch
1:45-3:00 Computer lab: Self-guided tutorials
3:00-6:00 Free time (computer lab remains open, also)
5:30 Cocktails
6:00-7:30 Dinner
7:30-9:00 Career Paths and NIDA Funding Opportunities for Research on the Genetics of
Addiction
Jonathan Pollock, Ph.D., National Institute on Drug Abuse/NIH
Wednesday, August 21st Pharmaco genetics and the addiction phenotype revisited
7:30-9:00AM Breakfast
9:00-10:00 Pharmacogenetics
Wade Berrettini, M.D., Ph.D., University of Pennsylvania
10:00-10:15 Break
10:15-11:15 Human Addiction Genetics
Laura Bierut, M.D., Washington University, St Louis
11:15-11:30 Break
11:30-12:30 Genetic Findings and Refinement of the Addiction Phenotype
Pamela Madden, Ph.D., Washington University, St. Louis
12:30-1:30PM Lunch
1:30-2:30 Twin Research – Methods for Understanding Addictions
Soo Hyun Rhee, Ph.D., University of Colorado
2:30-3:30 Open Discussion
3:30 -5:00 Jackson Laboratory Tour and Training Opportunities
5:00 -6:00 Cocktail Hour
6:00-8:00 Lobster Dinner
Thursday, August 22nd
7:30–9:30 AM Breakfast
Departures
