Gene transcription in yeast: From regulatory networks to mechanisms

Transcription, the first step in gene expression, plays a central role in many aspects of biology. Work in the unicellular yeasts, where powerful genetic, molecular and biochemical methods have been developed and exploited, has played an important role in this field and continues to do so today. This EMBO Conference brings together scientists applying a wide range of approaches, from “systems” to “atomic” levels, to address current challenges in the field.

Although the molecules and mechanisms involved in transcription and its regulation in eukaryotic organisms have been studied for several decades now, a detailed understanding of many fundamental issues is still lacking. Some of the topics that will be discussed at this meeting include:
Transcription at the single-cell level
Genome-wide views of transcription
RNA Polymerases – structure and function
Chromatin and transcription
Transcriptional responses to environmental signals
Regulatory mechanisms and gene networks
+ show speakers and program
Brenda Andrews
University of Toronto,
Title of talk: "Using yeast functional genomics to explore pathways regulating gene expression"

Steve Buratowski
Harvard Medical School,
Title of talk: “Coupling transcription with chromatin and mRNA processing”

Patrick Cramer
Ludwig Maximilian University of Munich,
Title of talk: "Structure-function studies of yeast transcription and genomic regulation"

Joachim Griesenbeck
University of Regensberg,
Title of talk: "Chromatin dynamics at the ribosomal DNA locus of S. cerevisiae"

Frank C. P. Holstege
University Medical Center Utrecht,
Title of talk: “Understanding regulatory circuitry through genome-wide analyses”

Philipp Korber
Ludwig Maximilian University of Munich,
Title of talk: "Nucleosome Positioning Mechanisms in Yeasts: Remodelers Rule, Remodelers' Rules, and Remodelers' Rulers"

Nevan Krogan
University of California,

Domenico Libri
Centre for Molecular Genetics,
Title of talk: "Orchestrating transcription termination and RNA degradation in the control of pervasive transcription"

Jason Lieb
Lewis-Sigler Institute for Integrative Genomics,
Title of talk: “Gene regulation in space and time”

John Lis
Cornell University,
Title of talk: "Mechanisms of Transcription Regulation Across Species: New Approaches and Findings

Jane Mellor
University of Oxford,
Title of talk: “Non-coding transcription in the yeast genome: Does it generate noise or it is a consequence of noise?”

Antonin Morillon
Institut Curie,
Title of talk: "Pervasive transcription, lessons from budding yeast"

Francesc Posas
Barcelona Biomedical Research Park, Pompeu Fabra University,
Title of talk: "Coordinated control of cell cycle progression and transcription in response to stress"

Frank Pugh
Penn State University,
Title of talk: “Gene regulation in space and time”

Oliver Rando
University of Massachusetts Medical School,
Title of talk: “Systematic functional and structural interrogation of chromatin’s role in a yeast stress response”

Eran Segal
Weizmann Institute of Science,
Title of talk: “Studying the regulatory code using thousands of designed regulatory sequences”

Jan Skotheim
Stanford University,
Title of talk: “Feedback-first regulation of cell cycle-dependent transcription”

Lars Steinmetz
Title of talk: “Uncovering layers of transcriptome complexity”

Francoise Stutz
University of Geneva,
Title of talk: “Role of antisense transcription in yeast gene regulation”

Jessica Tyler
The University of Texas,
Title of talk: “Chromatin assembly and disassembly “

Michel Werner
Insitute of Biology and Technology Saclay,
Title of talk: "Mechanisms of transcription activation by the Mediator complex"

Fred Winston
Harvard Medical School,
Title of talk: "Analysis of transcription and chromatin structure in spt mutants"

Jerry Workman
Stowers Institute for Medical Research,
Title of talk: “Histone modification and exchange during transcription”

14 Jun - 19 Jun 2014
Sant Feliu de Guixols
meeting website