Mechanisms of HIV Persistence: Implications for a Cure

Despite long-term control of HIV replication with cART, HIV persists as silenced integrated DNA in memory CD4 T cells, and possibly in other cellular reservoirs, including na?ve cells and macrophages. The path forward will require a detailed understanding of the mechanisms of viral latency which could lead to the identification of new drugs, and a better knowledge of the plasticity and dynamics of the main HIV cell reservoirs: CD4 T cells and macrophages. At the 2015 Keystone Symposia meeting on Mechanisms of HIV Persistence: Implications for a Cure, experts from both within and outside the HIV field will present findings from recent advances on immune mechanisms and therapeutic strategies which could lead to HIV cure.
+ show speakers and program
infectious diseases, immunology, pharmacokinetics, ADME, drug discovery, biologics, macromolecular chemistry, antigen presenting cells, inflammation, T cell biology, HIV

26 Apr - 1 May 2015
United States of America
meeting website