Short Course on Genetics of Addiction

This course emphasizes genetic applications and approaches to drug addiction research through methodological instruction based on literature, data sets and informatics resources drawn from studies of addiction related phenotypes. The course includes plenary sessions on major progress in addiction genetics, and discussion sessions in which students present their work for discussion on applications of genetic methods. Students will leave the course able to design and interpret genetic and genomic studies of addiction as they relate to their specific research question, and will be able to make use of current bioinformatics resources to identify research resources and make use of public data sources in their own research.

Funding for this conference was made possible (in part) by R13 DA 032192 from the National Institute on Drug Abuse. These views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the offical policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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Short Course on the Genetics of Addiction
August 14‐18, 2011
Contact: Erin McDevitt – Events and Meetings Planner
Sunday, August 14
4:00PM Registration and Dinner at Highseas
Monday, August 15
7:00AM Breakfast
8:15 Course Overview
Elissa Chesler, Ph.D., The Jackson Laboratory and  
Abraham Palmer, Ph.D., University of Chicago
8:30 Course Introductions
9:00    Overview of the Problem of Addiction and Goals of Genetic Studies
    Wade Berrittini, M.D., Ph.D., University of Pennsylvania
10:00    Break
10:30    Addiction as a complex trait; finding common and rare alleles
    David Goldman, M.D., National Institute of Alcohol Abuse and Alcoholism
11:30    Modeling Aspects of Addiction in the Laboratory Mouse
    Justin Rhodes, Ph.D., University of Illinois12:30 PM Lunch   
1:30 Addiction Studies in Laboratory Mice: Conditioned and Unconditioned Behavior
    Guy Mittleman, Ph.D., The University of Memphis
2:30 The Importance of the Laboratory Environment in Mouse Behavioral Genetics: the
“E” in G X E
John Crabbe, Ph.D., Oregon Health & Sciences University
3:30    Circadian Clocks, Clock Genes and Addiction
    Alan Rosenwasser, Ph.D., University of Maine
4:30    The Knockout Mouse Project
    Robert Taft, Ph.D., The Jackson Laboratory
6:00    Dinner
7:00 Evening Discussion: Student White Boards
Tuesday, August 16
7:00AM Breakfast
8:00    Selected Lines
    Tamara Phillips, Ph.D., Oregon Health & Science University  
9:00    Using Simple experimental crossing in mice to study complex traits
    Gary Churchill, Ph.D., The Jackson Laboratory
10:00    Break
10:30    Outbred populations and applications for complex traits  
    Abraham Palmer, Ph.D., University of Chicago
11:30    Systems genetics and analysis of complex traits in genetic reference populations.  
    Elissa Chesler, Ph.D., The Jackson Laboratory
12:30PM Lunch   
1:30 Microarray, Gene Expression and Next‐Generation Sequencing Analyses in Addiction
    Robert Hitzemann, Ph.D., OHSU2:30     Group Hike/Free Time
6:00 Dinner
7:00   Keynote Speaker: The Best‐laid Schemes O’ Mice and Men Gang Aft A‐Gley: or, Why
Won’t Mice Abuse Drugs?
John Crabbe, Ph.D., Oregon Health & Sciences University  
Wednesday, August 17
7:00AM Breakfast   
8:00    The Role of microRNAs in Nicotine and Other Addictions  
Ming D. Li, Ph.D., University of Virginia
9:00    Pharmacogenomics of Addiction
    Wade Berrettini, M.D., Ph.D., University of Pennsylvania
10:00    Break
10:30    Bioinformatics Approaches: Mouse Databases for systems genetics and
    mutant identification
    Carol Bult, Ph.D., The Jackson Laboratory
11:30    Using Public Genomic Databases to Study the Genetics of Human Disease
    Scott Saccone, Ph.D., WUSL
12:30PM Lunch
1:30 Integrating Genetic and Genomics of Addiction Across Species: & Workshop Introductions
    Elissa Chesler, Ph.D., The Jackson Laboratory
2:30 Open Labs – QTL Mapping with R/QTL, gene expression MGI, ODE, GeneNetwork, Hap
6:00    Dinner
7:00 NIH Funding Opportunities for Genetics of Addiction
    Louise Wideroff, Ph.D., National Institute on Drug AbuseThursday, August 18
7:00AM Breakfast
8:00    Historical prospective on alcoholism research
    David Goldman, M.D., National Institute of Alcohol Abuse and Alcoholism
9:00    Twin and Adoption studies Related to Addiction
    Carol Prescott, Ph.D., USC  
10:00    Break
10:30    GWAS and meta‐GWAS for Nicotine Dependence
Ming D. Li, Ph.D., University of Virginia  
11:30 Endophenotypes and Intermediate Phenotypes and Laboratory Measures Related to
Drug Abuse
Harriet de Wit, Ph.D., University of Chicago
12:30PM Lunch
1:30    Translational Research Models in Genetics and Addiction
    Caryn Lerman, Ph.D., University of Pennsylvania
2:30     Closing Summary Discussion
5:00     Cocktail Hour
6:00    Lobster Dinner
Friday, August 19

18 Aug - 23 Aug 2012

Bar Harbor
United States of America
meeting website