11th Annual Workshop on the Pathology of Mouse Models for Human Disease

This workshop provides a week of intensive training sessions in pathology and histopathology as well as didactic sessions in which particular disease areas and models will be discussed. Participants will have an opportunity to interact with a group of prominent mouse pathologists and geneticists from leading research institutions.

Topics and models to be covered include: nomenclature, basic mouse genetics, concepts of mouse model generation, approaches to working up mutant mice, role of pathologists at research institutions, systemic, hematopoietic, mammary, gynecologic, cutaneous, infectious and immune system pathology, embryology and cancer models.
+ show speakers and program
Annual Workshop on the Pathology of Mouse Models for Human Disease
September 23‐29, 2011
Contact: Erin McDevitt – Events and Meetings Planner 
Email: erin.mcdevitt@jax.org  
All events to be held at University Place Conference Center & Hotel unless otherwise specified
Friday, September 23rd
5:00‐7:00PM    Registration and Reception  
Saturday, September 24th
7:30‐8:00AM    Late Registration
8:30‐8:45    Introduction and Welcome  
Harm HogenEsch, Purdue University and George Sandusky, IU School of
8:45‐9:00  The Indiana Clinical and Translational Science Institute (CTSI)
Anantha Shekar and Lilith Reeves, IU School of Medicine
9:00‐10:00    Mouse Nomenclature and Basic Mouse Genetic Approaches I
Xavier Montagutelli,  Pasteur Institute
10:00‐10:30    Break
10:30‐11:30    Mouse Nomenclature and Basic Mouse Genetic Approaches II
      Xavier Montagutelli, D.V.M., Ph.D., Institut Pasteur
11:30‐12:30PM  Lunch    12:30‐1:30  How to Diagnose and Find Information on Strain Specific Diseases in
      John P. Sundberg, The Jackson Laboratory
1:30‐2:30  Computing on Pathology; Ontologies and Databases for the Capture and
Analysis of Pathology Data
      Paul Schofield, University of Cambridge
2:30‐2:45    Break
2:45‐3:45  Lymphoid Tissues
Harm HogenEsch, Purdue University
3:45‐4:45    Teeth
Peter Vogel, St. Jude Children's Research Hospital
Sunday, September 25th
8:30‐9:30AM    Allergic Diseases
Harm HogenEsch, Purdue University
9:30‐10:30  PI/Pathologist Interface: Interpretation of Complex Phenotypes in
Genetically Modified Mice
Alexander Yu Nikitin, Cornell University College of Veterinary Medicine
10:30‐10:45    Break
10:45‐11:45    Eyes
Peter Vogel, St. Jude Children's Research Hospital
11:45‐1:15PM  Lunch   ‐ slide/case presentations by workshop participants  
1:15‐2:15  Approaches to Modeling Human Ovarian and Mammary cancers
Alexander Yu Nikitin, Cornell University College of Veterinary Medicine
2:15‐3:15  Mouse Models, Stem Cells and Cancer
   Alexander Yu Nikitin, Cornell University College of Veterinary Medicine
3:15‐3:30    Break
3:30‐4:30  The Role of TNF in Colitis and Colitis‐Associated Colon Cancer
   Yava Jones, Purdue University
   Monday, September 26th
8:30‐9:30AM  Access to Genetically Engineered Mouse Resources – What You Need
to Know!  
Oleg Mirochnitchenko, NCRR, NIH
9:30‐10:30  Approaches to the Pathology of the Central Nervous System
    William Jordan, VetPath Services  
10:30‐11:00    Break
11:00‐12:00PM  Mouse Models of Alzheimer Disease
Bruce Gitter, Covance  
12:00‐2:00    Lunch  ‐ slide/case presentations by workshop participants 
2:00‐3:00  Mouse Modeling of Psychiatric Disordres
Alexander Niculescu, III, M.D., Ph.D., Indiana University School of Medicine  
3:00‐4:00  Evaluation of the Placenta and Embryo
Jerrold Ward, Global Vet Pathology   
4:00‐5:00  Free Time
4:00‐5:00  Tour of the Indiana Medical History Museum
Tuesday, September 27th
8:30‐11:30AM    Workshop Rotations:  
1. Microscopy
Ken Dunn, IUSM, Imaging Center
2. Aperio and IU Tissue Bank
Jeff Hansen, Lilly, Mike Esterman, Consultant, and Colleen Mitchell,
Daily Operations Manager, Tissue Bank
3. Electron Microscopy
Mike Goheen, Indiana University Health Path Labs
4. Radiology Imaging
Paul Territo, IUSM
11:30‐1:00PM  Lunch  ‐ Disussion: Veterinary Pathology Support at Medical Research
Institutions  (Jerrold Ward, Piper Treuting, Jerry Rehg)   
1:00‐2:00  Use of Mouse Models to Study Myocardial Repair
   Loren Field, IU School of Medicine2:00‐3:00  Tumor Pathology  
Jerrold M. Ward, Global VetPathology
3:00‐3:15    Break
3:15‐4:15    Inflammatory Bowel Disease Models
Piper Treuting, University of Washington
4:15  Depart for Indianapolis Motor Speedway (tour and dinner)
Wednesday, September 28th
8:30‐9:30AM    Immunohistochemistry  
George Sandusky, IU School of Medicine
9:30‐10:30  Lyphomas
Jerry Rehg, St. Jude’s Children’s Hospital
10:30‐11:00    Break
11:00‐12:00PM  Sarcomas
Jerry Rehg, St. Jude’s Children’s Hospital
12:00‐1:00    Lunch    
1:00‐2:00  Clinical Pathology  
Armando Irizarry, Eli Lilly
2:00‐3:00  Modeling Pancreatitis and Pancreatic Cancer in Mice
Steve Konieczny, Purdue University  
3:00‐3:30    Break
3:30‐4:30    Mouse Models of Type 2 Diabetes Mellitus
Carmela Evans‐Molina, IU School of Medicine
Thursday, September 29th
8:00‐9:30AM    Diseases of Skin and Adnexa
John Sundberg, The Jackson Laboratory  
9:30‐10:30    Environmental Influences on Bone Formation
Russell Main, Purdue University  10:30‐11:00    Break
11:00‐12:00  Mouse Models of Osteoporosis
Linda Ma, Lilly  
12:00  Lunch and Adjourn

9 Sep - 16 Sep 2012

Bar Harbor
United States of America
meeting website