Weak protein-ligand interactions: new horizons in biophysics and cell biology

This meeting will emphasize technological advances and applications in studying weak protein-ligand interactions, using a variety of cutting-edge biophysical, biochemical, and cell biology techniques including:

NMR Spectroscopy
X-Ray Crystallography
Co-immunoprecipitation and Pull-down
In Vivo Fluorescence Resonance
Energy Transfer (FRET)
Yeast Hybrid and Phage Display
Chemical Crosslinking
Mass Spectroscopy

Small Angle Light Scattering
Computational Docking
Single Molecule Fluorescence
Atomic Force Microscopy
Magnetic Tweezers
Surface Plasmon Resonance
Isothermal Calorimetry Titration
The meeting is co-sponsored and co-organized by the Biophysical Society and the Institute of Biophysics of Chinese Academy of Sciences.
+ show speakers and program
Alexandre Bonvin, Utrecht University, The Netherlands
Modelling Weak Biomolecular Interactions by Information-driven Docking

Marie-France Carlier, National Center for Scientific Research, France
Multifunctional Regulation of Actin Assembly by WH2 Domains

Jack Greenblatt, University of Toronto, Canada
Protein Interaction Networks for Bacteria, Yeast, and Man: Insights into Membrane Biology and Transcriptional Regulation

Angela Gronenborn, University of Pittsburgh, USA
Sweet Encounters - Protein: Sugar Recognition

Dorit Hanein, Sanford-Burnham Medical Research Institute, USA
Structural Mapping of the Protein Universe; One Cell at a Time

Lan Huang, University of California, Irvine, USA
Developing Proteomic Approaches to Define Protein-Protein Interactions

Hualiang Jiang, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China
Predicting Affinity and Kinetics of Ligand-Protein Binding: Methodology Development and Application in Drug Design

Tom Kerppola, University of Michigan, USA
Visualization of Transient Interactions Using gelFRET Analysis and Bimolecular Fluorescence Complementation

Carolyn Larabell, University of California, San Francisco, USA
Putting Molecules in Context with Correlated Cryo Confocal and X-Ray Tomography

Gil Lee, University College Dublin, Ireland
Magnetic Tweezers-based Force Clamp: Reveals Mechanically Distinct Domain Interactions in apCAM Bonds

Rong Li, Stowers Institute for Medical Research, USA
Mechanism of Actin-based Force Generation During Asymmetric Cell Division

Yunyu Shi, University of Science and Technology of China, China
Cooperation of Escherichia Coli Hfq Hexamers in DsrA Binding and ATP Hydrolysis

Dmitri Svergun, European Molecular Biology Laboratory, Germany
Structural Studies of Protein-Ligand Interactions in Solution by Small-Angle X-ray Scattering

Gerhard Wagner, Harvard University, USA
Elucidating and Inhibiting Weak Interactions in Gene Expression

Erich Wanker, Max Delbrück Center for Molecular Medicine, Germany
What Small Molecules Can Do with Aggregation-Prone Polypeptides

Clare Waterman, National Institutes of Health, USA
The Focal Adhesion Molecular Clutch

Mingjie Zhang, Hong Kong University of Science and Technology, China
Assembling Highly Specific Signaling Complexes by Multiple Weak but Coincident Interactions

14 Oct - 18 Oct 2012

meeting website