5th Conference on Advances in molecular mechanisms underlying neurological disorders

Research into the fundamental mechanisms underlying neurological disease processes is an important and rapidly developing area, with huge potential significance, not least for developing novel therapeutic approaches. This joint meeting between the European Society for Neurochemistry and the Biochemical Society will bring together basic and clinical scientists, early-career and senior investigators to explore the recent advances in this area.

The programme includes three full days of science arranged in a number of plenary lectures, symposia and mini-symposia with talks from world-leading scientists as well as poster sessions, and opportunities for oral presentations selected from among the submitters of abstracts. The social events in this world heritage city which accompany the scientific programme will promote interactions between all participants at the meeting. Networking and social activities include a reception at the Ancient Roman Baths and a conference dinner. We look forward to welcoming you to Bath in 2013.


Protein degradation pathways and neurodegeneration
RNA processing in neurodegenerative disease
Neuronal protein traffic in health and disease
Mini-symposia/workshops to be proposed by participants

+ show speakers and program
David Attwell (University College London, UK)
Neurotransmitter actions on oligodendrocyte lineage cells in health and disease

Daniel Geschwind (University of California, Los Angeles, USA)
Gene expression Networks

Michael Ehlers (Pfizer, USA)
The Thudichum Medal Lecture

Britta Engelhardt (University of Bern, Switzerland)
Immune-blood brain barrier interactions

Symposium 1: Protein degradation pathways and neurodegeneration
Chaired by David Rubinstzein (University of Cambridge, UK)

Ana Maria Cuervo (Yeshiva University, USA)
Chaperone mediated autophagy and neurodegeneration

Daniel Finley (Harvard University, USA)
Proteasome activation and therapeutic strategies

David Rubinsztein (University of Cambridge, UK)
Macroautophagy and neurodegeneration

Ralph Nixon (New York University, USA)

Autophagy and Alzheimer’s Disease

Symposium 2: RNA processing in neurodegenerative disease
Chaired by Jackie de Belleroche (Imperial College London, UK)

Jernej Ule (University of Cambridge, UK)
How can aberrant protein-RNA interactions lead to neurologic diseases?

Christian Haass (Ludwig Maximilians University Munich, Germany)
Zebrafish models for uncovering function of mutant TDP43/fus

David Mann (University of Manchester, UK)
TDP43 and fus in human neuropathologies

Francisco Baralle (International Centre for Genetic Engineering and Biotechnology, Italy)
The role of the hnRNP TDP 43 in the pathogenesis of ALS and FTLD

Mini-symposium/Symposium: Neuronal protein traffic in health and disease
Chaired by Jeremy Henley (University of Bristol, UK)

Casper Hoogenraad (Utrecht University, The Netherlands)
Mechanisms of polarised trafficking

Jose Esteban (University of Madrid, Spain)
AMPAR trafficking in spines

Daniel Choquet (University of Bordeaux, France)
Bridging glutamate receptor nanoscale organization and function

Antoine Triller (Inserm, France)
Title TBA

23 Jun - 26 Jun 2013
University of Bath
United Kingdom
meeting website