Microscopy & Microanalysis 2012 Meeting

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BO1: Microbial Biofilms - The Good, The Bad, and The Ugly
Janet H. Woodward, Alice Dohnalkova

Invited Speakers:
Pamela Lloyd, UES, Inc., Dayton
Jeffrey McLean, J. Craig Venter Institute, San Diego
Ryan Hunter, California Institute of Technology
Brenda Little, Naval Research Laboratories
This symposium will cover current research on biofilms in human health and diseases, industrial applications, and in the environment. Topics can include:

Biofilm structure and function
Cell signaling and quorum sensing in biofilm environments
Biofilm motility and mechanics
Biofilm dynamics
B02: Microscopy and Analysis in Forensic Science

The symposium will focus on:

Microscopy of impression evidence with a specific emphasis on the techniques that can be used for firearms identification
Scanning and confocal microscopy applications, which provide specific advantages over conventional optical microscopy.
Precision and reproducibility of microscopic and microanalytic techniques for evidence collection and comparison
Sample collection and preparation techniques for proper handling and analysis of evidentiary material
B03-Structure of Membrane-shaping Proteins
Jenny E. Hinshaw, William A. Prinz, Jason A. Mears

Invited Speakers:
Vinzenz Unger, Northwestern University
Leonid Chernomordik, NICHD, National Institutes of Health
Scott Stagg, Florida State University
Carlson Lars-Anders, NIDDK, National Institutes of Health
Marjin Ford, University of California — Davis
Michael Stowell, University of Colorado — Boulder
Each cellular organelle has a unique shape that contributes to its function. The Golgi consists of membrane stacks, the endoplasmic reticulum is a network of membrane tubules and sheets, while mitochondria are complex double-membrane organelles with various spherical and elongated shapes. Membrane trafficking between the organelles and the plasma membrane is actively occurring by membrane fission and fusion events, and yet the organelles maintain their shape. In recent years, numerous proteins have been identified that play a crucial role in maintaining organelle structure, and the communication between organelles and the plasma membrane. This symposium will discuss the proteins that are involved in these dynamic membrane events. Various methods are used for these studies including, electron microscopy, X-ray crystallography, freeze-fracture and fluorescence microscopy.

B04: 3D Structure and Ultrastructure of Cells, Organelles and Macromolecules
Elizabeth R. Wright, Teresa Ruiz, Kelly Lee

Invited Speakers:
Esther Bullitt, Boston University School of Medicine
Grant Jensen, California Institute of Technology
Arne Moeller, The Scripps Research Institute
Kenneth Taylor, Florida State University
Xing Zhang, University of California — Los Angeles
Michael Radermacher, University of Vermont
Our understanding of the 3D structure and functional subtleties of cells, microorganisms and macromolecular assemblies has experienced great advances through recent developments of EM techniques and hybrid methodologies. This symposium highlights structural and ultrastructural studies of cells, microorganisms and macromolecules using electron microscopy techniques (e.g. tomography; crystallography; single-particle analysis; helical reconstruction) singly or combined with other structural methods (e.g. X-ray crystallography; X-ray tomography; atomic force microscopy). Topics will include: eukaryotic and prokaryotic architecture; cellular metabolism; cell division and protein translation; cellular secretion, adhesion and motility; cell-cell communication and signaling; virus structure and virus-host interactions; structure and function of macromolecular assemblies.

B05: Visualization, Localization and Dynamics of Cellular Components
Christopher L. Berger, Diane S. Lidke, Josh E. Baker

Invited Speakers:
Paul Wiseman, McGill University
Raimund Ober, University of Texas Southwestern Medical Center
Louis Hodgson, Albert Einstein College of Medicine
Ammasi Periasamy, University of Virginia
Ajit Joglekar, University of Michigan
Our understanding of the localization, intramolecular interactions, and dynamics of macromolecular complexes within the cell or cellular components has grown in tandem with the development of quantitative fluorescence microscopy techniques. Recent advances in fluorescence microscopy have dramatically increased both spatial and temporal resolution, allowing for direct visualization of biological processes. This symposium will highlight advances in these techniques that have provided new insight into the structure and dynamics of cell signaling pathways, the cytoskeleton and cell motility, and intracellular membrane systems.

B06: Utilizing Microscopy for Research and Diagnosis of Diseases in Humans, Plants and Animals
Patricia E. Kysar, Irene Piscopo, Jay Jerome, Cindy Smith

Invited Speakers:
Sara Miller, Duke University Medical Center, Dept of Pathology
George Perry, University of Texas College of Science
Rich Goodwin, University of South Carolina School of Medicine
Wilma Lingle, The Mayo Clinic
E. Ann Ellis, Texas A&M University
Rich Giberson, Ted Pella, Inc.
Carolyn Larabell, University of California — San Francisco
Johnny Carson, UNC-Chapel Hill, Center for Environmental Medicine
Microscopy is not only useful, but critically important in the ongoing research, detection, diagnosis and treatment of disease. Advances that improve rapid and accurate detection and treatment often involve the use of various microscopic applications. Various microscopy and imaging approaches in diagnostics and research of human, plant and animal specimens, provide us with an improved ability to research disease origin, development and response. This is an opportunity to share information on the investigation of pathogens of cells, tissues and entire organisms in clinical, diagnostic and research laboratories. Emphasis will be placed on both rapid detection and improvements in methodologies.

B07: Microscopy, Microanalysis and Image Analysis in the Pharmaceutical Sciences
Alejandra Camacho, Beverly E. Maleeff, Phoebe L. Stewart

Invited Speakers:
Michel Deschuyteneer, GlaxoSmithKline Biologicals, Belgium
Greg Haugstad, University of Minnesota
Florian Formanek, L'Oreal, France
Jennifer Barton, University of Arizona
Pharmaceutical research and development laboratories are at the forefront of science and have developed specialized technologies and themes that are of particular value to microscopists in industry. This symposium will present applications of microscopy associated techniques to biological and materials science problems that arrive during drug discovery, formulation and production. In addition to presentations by invited speakers, an informal forum will be provided for sharing of thoughts and strategies related to regulatory and other issues faced in our laboratories. Contributed papers from industry, government or academia for platform or poster presentation on related topics are also welcome.

P01: Electron Microscopy/Spectroscopy of Energy-Related Materials
Paulo J. Ferreira, Yimei Zhu, Grace Burke

Invited Speakers:
Jin Zou, University of Queensland, Australia
Tsukasa Hiramaya, Japan Fine Ceramics Center
Jianyu Huang, Sandia National Laboratories
David Muller, Cornell University
Chung Sung Yoon, Inha University, Korea
Javier Bareno, Argonne National Laboratory
Stephen Pennycock, Oak Ridge National Laboratory
Andrew Minor, University of California — Berkeley
Steve Claves, Bettis Laboratory
With an ever-increasing demand in clean and efficient energy research and the development of new energy materials, there is currently a significant effort in developing novel electron microscopy imaging, diffraction and spectroscopy methods for determining the atomic/nano structure and chemical composition of various materials for energy conversion and storage. On the basis of these developments, it seems appropriate to review the field in a manner that would be useful for the areas of alternative energy materials. The goal of this symposium is to bring together a wide variety of researchers with interests in electron microscopy imaging, electron diffraction, electron spectroscopy and computer simulations applied to batteries, fuel cells, photovoltaics, photocatalysts, supercapacitors, and nuclear materials.

P02: Structural, Chemical and Physical Properties of Carbon-based and Related Nanomaterials
Raul Arenal, Jannik C. Meyer, Sebastian Osswald

Invited Speakers:
Kazu Suenaga, AIST, Japan
David Muller, Cornell University
Dmitri Golberg, NIMS, Japan
Markus Morgerstern, RWTH Aachen, Germany
Florian Banhart, IPCMS, University Strasbourg, France
Andrei Khlobystov, University of Nottingham, UK
Yuri Gogotsi, Drexel University
Alejandro Lopez-Bezanilla, Oak Ridge National Laboratory
Carbon-based nanostructures such as fullerenes, nanotubes, nanodiamond, and graphene are attractive materials due to their unique properties and wide range of potential technological applications. While electron microscopies (TEM, STEM, SEM) are essential and powerful techniques for studying carbon nanomaterials at the (sub)nanometer scale, the coupling of electron microscopy with other characterization techniques, including Raman and infrared spectroscopy, XPS, and scanning probe microscopy is increasingly utilized to fully investigate these materials and provide deeper insights into their physical and chemical properties. This symposium focuses on microscopy-based studies that employ these techniques to study nanostructures, particularly carbon, boron, and nitrogen-containing nanomaterials.

P03: Hybrid (Soft-Hard) Materials and Interfaces
Vinayak P. Dravid, Richard D. Leapman, Derk Joester

Invited Speakers:
Harald Ade, North Carolina State University
Matt Libera, Stevens Institute of Technology
Alexandra Porter, Imperial College, UK
Alexandre Gloter, University of Paris, France
Eli Sone, University of Toronto, Canada
Stephen Vogt, Argonne National Laboratory
Roger Wepf, ETH Zurich, Switzerland
Roland Kroger, University of York, UK
David Ginger, University of Washington
Derk Joester, Northwestern University
The symposium will address the specific challenges in specimen preparation, microscopy and analysis presented by hard-soft hybrid structures and interfaces, including Improving specimen preparation for hybrid structures and interfaces, Imaging and analysis in the wet and pristine state (e.g., fluidic-cell development and applications), quantitative chemical imaging and tomography in hybrid systems. We will be addressing structural hierarchy in hybrid materials: multi-scale and correlative imaging approaches, as well as looking at hybrid materials and interfaces across the disciplines: bio-inspired materials, biominerals, polymer-composites, tissue scaffolds, surface coatings, functionalized nanomaterials, and others.

P04: Microscopy and Microanalysis of Joining and Coating Materials
Steven R. Claves, Chad M. Parish, Donald F. Susan

Invited Speakers:
Kinga Unocic, Oak Ridge National Laboratory
David Hoelzer, Oak Ridge National Laboratory
Stepheni Liu, Colorado School of Mines
Richard Fonda, Naval Research Lab
Badri Narayanan, Lincoln Electric
Howie Jin, ExxonMobil
Joining and coating technologies, such as welding, soldering, brazing, and cladding, are used to join multiple pieces into components and to protect the resulting component surfaces from wear and corrosion. These processes often involve complex, multi-component phase transformations, which can produce intricate micro- and nanostructures; characterization of these microstructures is required to understand how the joining and coating processes influence the properties of the materials in service. This symposium will cover non-destructive and destructive microscopy and microanalysis of advanced joining and coating processes, including a broad range of techniques from macroscale optical metallography to single-atom high resolution imaging.

P05: High-resolution Microscopy and Microanalysis of Meteorites, Minerals and Aerosols
John Armstrong , David Smith, Lindsey Keller, David Bell

High resolution electron microscopy and x-ray microanalysis have played major roles in the characterization of geological, extraterrestrial and environmental materials since their invention. High resolution electron microscopy has been responsible for moving the study of minerals from the macro to the atomic level. X-ray microanalysis has proven to be the most accurate analytical method for determining the elemental composition of geological and extraterrestrial specimens at the micro- and now nano-scale. For over forty years, Peter R. Buseck in the Chemistry Department and School of Earth and Space Exploration has been in the forefront of research in combining high resolution electron microscopy and x-ray microanalysis in the study of minerals, meteorites and environmental aerosols. This symposium will focus on the important contributions that have been and are continuing to be made by the synergistic use of these imaging and analysis procedures in studies of the solid materials of our solar system as demonstrated by Peter Buseck, his many students and colleagues, and those influenced by them.

P06: Failure Analysis of Structural Materials
J. Martinez, D. Dennies

Invited Speakers:
Donald Susan, Sandia National Laboratories
Johnny Golden, The Boeing Company
Rudy Villa, United States Air Force
Michelle Othon, GE Global Research Center
Failure analysis is an important function crossing all disciplines. This symposium will include real-world applications and research case studies to determine the root cause in the failure of structural materials. In particular, this symposium will highlight the application of all materials used as structural members and components. Any and all optical, scanning, transmission, and microanalytical techniques used throughout the investigation will be discussed. Topics covered include metal fatigue and fracture, environmental factors such as corrosion, embrittlement, overload, biomaterials/medical implants, semiconductor, multi-mode failures, etc. Contributions are encouraged from industry failure analysts and researchers active in any of these areas.

P07: Microscopy and Analysis of Quantum Structures and Devices
Brendan Foran

Invited Speakers:
Michael Johnson, Arizona State University
Michael Yakes, Naval Research Lab
Andreas Rosenauer, University of Bremen, Germany
Jason Kawasaki, University of California — Santa Barbara
Rachel Goldman, University of Michigan
Quantum wells, wires and dots enable solid state device technologies requiring electronically and spatially well defined electronic states. The nano-scale size of these structures, and associated importance of interfacial states, strain and variation in local composition all make quantitative analysis and microscopy crucial for accurate interpretation of structure-property relationships necessary for understanding and improving materials performance. This symposia is focused on sharing recent results on microscopy and microanalysis of quantum structures and could include techniques ranging from TEM methods including HRTEM and geometric phase analysis, STEM-EELS or EDXS, SEM methods including EBIC and CL as well as scanning probe techniques such as cross-sectional STM, as these are used to improve understandings of the physics and chemistry involved in process optimization and functionality of devices.

A01: Applications of Aberration-Corrected STEM and SEM
K. Andre Mkhoyan, Paul M. Voyles, Joseph R. Michael

Invited Speakers:
Philip Batson, Rutgers University
Gianluigi Botton, McMaster University, Canada
Yimei Zhu, Brookhaven National Laboratory
Koji Kimoto, NIMS, Japan
Sandra Van Aert, University of Antwerp, EMAT, Belgium
Access to aberration-corrected STEM and SEM instruments is increasingly common. This symposium will seek answers to the question "What new scientific or technological problems can we solve with these new tools?" Abstracts are therefore solicited on applications of aberration-corrected STEM and SEM to the characterization of the materials and nanostructures for applications in nanotechnology. Techniques of interest include imaging, especially quantitative imaging and simulation, EELS and EDS, especially high-current, high-rate, and dense spectrum images, and CBED. Applications areas of interest include but are not limited to nanoelectronics, low-dimensional structures such as nanoparticles or single-atomic layer materials, and catalysis.

A02: Robert Gray Memorial Symposium on Metallography of Reactive Materials
Jaret J. Frafjord, Rod McCabe, Steve Dekanich

Invited Speakers:
Jane Howe, Oak Ridge National Laboratory
Bob Crouse, Oak Ridge National Laboratory (Ret.)
Ann Kelly, Los Alamos National Laboratory
This symposium will honor the work of Robert Gray, who helped establish the Metallography Group at the Oak Ridge National Laboratory in East Tennessee. Presentations will discuss work on the metallographic and sample preparation of reactive and radioactive materials. Many metals and alloys are extremely challenging to prepare because they react with the atmosphere or water during polishing or analysis. Some metals are radioactive and require special procedures to prevent contamination and radiation hazards. This symposium will not be limited to metals but will also discuss challenging reactive materials such as hydrides, battery materials, and explosives.

A03: TEM Phase Contrast Imaging in Biological and Materials Science
Mike Marko, Radostin Danev

Invited Speakers:
Robert Glaeser, Lawrence Berkeley National Laboratory
Fu-Rong Chen, National Tsing Hua University, Taiwan
Wah Chiu, Baylor College of Medicine
Kuniaki Nagayama, Okazaki Institute for Integrative Bioscience, Japan
Andreas Walter, Max-Planck Institute for Biophysics, Germany
Rasmus Schröder, University of Heidelberg, Germany
Yoshiyuki Fukuda, Max-Planck Institute for Biochemistry, Germany
Dagmar Gerthsen, Karlsruhe Institute of Technology, Germany
Marek Malac, University of Alberta, Canada
Conventional TEM phase-contrast imaging limits maximum information transfer to a narrow band of spatial frequencies. This can be avoided by in-focus imaging with a physical phase plate. The theory, construction, and practical use of phase plates will be explored. In biological cryo-TEM, high-contrast, high-resolution imaging at low electron dose is facilitated. In materials science, the combination of a physical phase plate with tunable Cs offers an unparalleled opportunity for characterization of both atomic details and larger structures. Since the number of laboratories starting to employ phase-plates is growing, this will be a timely opportunity to learn and to share experiences.

A04: 3D Structure Determination in Physical and Biological Sciences
Daniela Nicastro, Peter Nellist

Invited Speakers:
Sara Bals, University of Antwerp, Belgium
Stefan Zaefferer, Max Planck Institute for Iron Research
Ilke Arslan, University of California — Davis
Thomas Marlovits, Institute of Molecular Biotechnology, Austria
Michael Stowell, University of Colorado — Boulder
James Anderson, University of Utah
This symposium will cover:

Integrative cell biology: 3D-EM combined with other structural techniques (e.g. SAXS), fluorescence microscopy (CLEM), proteomics and genetics.
Serial-section 3D-EM approaches, e.g. confocal STEM, FIB-SEM and axial tomography.
Pushing the resolution in structure determination of macromolecules: from subtomogram averaging to femtosecond X-ray protein nanocrystallography.
Advances in 3D reconstruction and element mapping, e.g. energy-filtered, HAADF, and holographic electron tomography.
A05: Laser Mediated Processes for High-Contrast, High-Resolution, Ultrafast and In-situ TEM
Nigel D. Browning, Geoffrey H. Campbell, Claus Ropers

Invited Speakers:
Nobuo Tanaka, Nagoya University, Japan
Yoshie Murooka, Osaka University, Japan
Dwayne Miller, University of Hamburg, Germany
Andreas Schroeder, University of Illinois &mash; Chicago
Tom Kelly, Ametek
Bryan Reed, Lawrence Livermore National Laboratory
Federico Rosei, University of Quebec, Canada
The aim of this symposium is to provide a forum to discuss new developments involving the integration of laser technologies into electron microscopy. Contributions are encouraged that concern all aspects of the use of optical excitation — including the generation of the electron beam through photoemission, phase plate technologies, optical in-situ experiments, and electron energy loss spectroscopy. Advanced applications of these approaches to biological systems, solid state materials and nanostructures are particularly welcomed. Finally, the development of new methods for processing, analysis and simulation of images, diffraction patterns and spectra will be a focus of this symposium.

A06: Focused Ion Beam Instrumentation & Applications for Physical and Biological Sciences
Keana Scott, Lucille Giannuzzi, Nabil Bassim

Invited Speakers:
Michael Marsh, Visualization Science Group
Michael Ramsey, University of North Carolina — Chapel Hill
Brent Gila, University of Florida
Jaroslav Liruse, Tescan, Czech Republic
Eduardo Rosa-Molinar, University of Puerto Rico-Rio Piedras
Carl Sondergeld, Oklahoma University
Focused ion beam instruments have become essential tool in many fields due to their versatility and three dimensional processing capabilities. With the recent advances in FIB instrumentation, detector technology and analysis techniques, FIB application space now spans from semiconductor industry to materials science to biology. In this symposium, we encourage abstracts on all aspects of focused ion beam technology and its use to further the understanding of the physical and biological sciences. Topics such as theoretical or experimental work on ion-solid interactions, FIB-based specimen preparation, processing and fabrication methods and FIB-based 2D and 3D analyses of hard and soft materials are welcome. Advances in new FIB instrumentation or methods such as light ion sources, high current ion sources, mass filtered ion sources or low energy ion milling are also of interest.

A07 Super-resolution Microscopy — Principles and Practice
Hari Shroff. Jim Galbraith, David Giovannucci

Invited Speakers:
Andrew York, NIBIB, National Institutes of Health
Keith Lidke, University of New Mexico
Luke Lavis, Janelia Farm
Joerg Bewersdorf, Yale University
Cathy Galbraith, National Institutes of Health
Particular areas of focus will include:

Dynamic cellular processes
Exploring biological structures using superresolution microscopy
Multi-dimensional super resolution imaging (3D or multi color)
Analysis approaches for extracting biologically relevant information from super-resolution data
Probes for super-resolution imaging
A08: Channeling Effects in Microscopy and Microanalysis
Yoosuf N. Picard, Ian M. Anderson , Martin A. Crimp

Invited Speakers:
David C. Bell, Harvard University
Heiner Jaksch, Carl Zeiss NTS, Germany
Leslie Allen, University of Melbourne, Australia
Marc de Graef, Carnegie Mellon University
Nestor J. Zaluzec, Argonne National Laboratory
Patrick J. Phillips, Ohio State University
Huolin L. Xin, Lawrence Berkeley National Lab
Channeling is inherent to the propagation of radiation in crystalline matter, a fundamental consequence of the anisotropy imposed by long-range atomic order. Channeling is the basis for diffraction-based structural characterization methods, such as CBED, electron microdiffraction, and EBSD, and is fundamental to atomic-resolution microanalysis. Channeling also provides contrast generation mechanisms for imaging grain structure, structural defects and strain in SEM-BSE/-ECCI and HIM-/FIB-SE imaging and the basis for sublattice occupation measurements by ALCHEMI. This symposium seeks to bring researchers with expertise in diverse techniques and instrumentation together to discuss the role, effects, and exploitation/mitigation of channeling for microscopy and microanalysis.

A09: Measurement and Visualization of Mechanical Behavior at Micro and Nano-scales
Peter Hosemann, Andrew Minor

Invited Speakers:
Manuel Pouchon, Paul Scherrer Institute, Switzerland
Nathan Mara, Los Alamos National Laboratory
Xiaoxu Huang, Risø National Laboratory, Denmark
Ben Larson, Oak Ridge National Laboratory
Mike Uchic, Wright-Patterson AFB
Dan Gianola, University of Pennsylvania
Cynthia Volkert, University of Göttingen, Germany
Gerhard Dehm, Montan University of Leoben, Austria
This symposium will focus on new experimental tools and methods that allow us to access information on the microstructure and state of deformation in materials with spatial resolutions ranging from microns down to nanometers. It is important to consider the measurement of mechanical properties in conjunction with methods for visualizing a material's microstructure and its evolution during processing or deformation. Small-scale mechanical techniques such as ex-situ and in-situ compression, tension, bending or indentation generate fundamental insight into deformation processes that can be paired with structural techniques such as atom-probe tomography, electron tomography, synchrotron tomography and related digital image correlation methods.

A10: Helium Ion Microscopy
David Bell, David C. Joy, Vincent S. Smentkowski

Invited Speakers:
Andre Beyer, University of Beilefeld, Germany
John Notte, Carl Zeiss NTS
Emile van Veldhoven, TNO, Netherlands
Mike Postek, National Institute of Standards & Technology
Adam Hall, University of North Carolina — Greensboro
Daniele Pickard, National University of Singapore, Singapore
Stuart A. Boden, University of Southampton, UK
Rick Livengood, Intel
The Helium Ion Microscopy has now come of age with multiple instruments producing new and exciting results. HIM is capable to image conductive as well as insulating samples without special treatment, and allows imaging of unstained biomaterials and cell surfaces. Helium ion lithography is routinely producing ultra narrow line widths. HIM has the potential to become a routine microscopy tool for material science and nanotechnology, as well as in life science and biotechnology. This symposium covers all aspects of HIM related science, ranging from Helium ion optics and contrast mechanisms to materials imaging, bioimaging and lithography. Contributions covering fundamentals of HIM imaging and lithography as well as from HIM applications are very welcome.

A11: Correlative Microscopy and Chemical Imaging
Alice Dohnalkova, Xiaokun Shu, Carol Hirschmugl

Invited Speakers:
Chris Jacobsen, Argonne National Laboratory
Jack Griffith, University of North Carolina — Chapel Hill
Tom Deerinck, University of California — San Diego
This symposium will cover multifaceted approaches of current research on obtaining high resolution structural information in conjunction with the compositional information, including spectroscopy-based imaging methodologies, chemical cellular responses and materials characterization.

A12: Surface and Subsurface Analysis
Vincent S. Smentkowski, John A. Chaney, Supanan Seraphin, Igor Sokolov

Invited Speakers:
Chanmin Su, Bruker
Craig Prater, Anasys Instruments
Felix Kollmer, IonTof, Germany
Tim Nunney, Thermo Scientific
John Hammond, PHI
Chris Moffitt, Kratos
Tom Kelly, Cameca
Bob Opila, University of Delaware
Zoya Leonenko
Sergey Magonov, NT MDT
Robert Ross, ASU
Franklin Tao, Notre Dame
Anthony Muscat, University of Arizona
Christopher Szakal, NIST
Miriam Unger, University of Wisconsin @ Milwaukee
Jean Paul Allain, Purdue
Kai Wu, University of Beijing
Surface properties (composition, uniformity, thickness, etc) dictate the performance of many materials and biological systems. The surface analyst is asked to detect and image species present in ever-lower concentrations and within ever-smaller spatial and depth dimensions. This symposium will emphasize state of the art surface analytical instrumentation, advanced data analysis tools, the use of complementary surface analytical instrumentation to perform a complete analysis of complex materials and/or biological systems, and surface analytical challenges. Contributed papers on surface analysis are solicited for both platform and poster presentation we are especially interested in presentations on AES, XPS, ISS, SIMS, APT, SPM and low voltage SEM.

A13: Micro X-Ray Fluorescence
Eric Telfeyan, Jeffrey M. Davis, MSCE, EIT

Invited Speakers:
Heike Soltau, PHSensor GMBH
Paul Kotula, Sandia National Laboratories
Michael Haschke, Bruker Nano GMBH, Germany
Sergey Mamedov, Horiba Jobin Yvon, Inc.
Andrew Lee, EDAX
From materials science to biology to art conservation, obtaining spatially resolved elemental information can be vital. Micro X-Ray fluorescence provides high sensitivity elemental distribution information using low vacuum or air operation and minimal sample preparation without destroying the sample. In part for these reasons, X-ray compositional imaging using synchrotron and laboratory µXRF instruments has seen renewed interest in the microscopy field. This symposium will focus on µXRF analysis with topics including novel applications, advanced instrumentation, and advanced data processing. Papers discussing synchrotron and laboratory scale instruments and their use in materials science, semiconductors, biology, art conservation, and chemistry are encouraged.

A14: Quantification from the Micro- to Sub-nano Scales: Pushing the Limits.
Paul G. Kotula, Gianluigi Botton, Emmanuelle Marquis

Invited Speakers:
Ty Prosa, Cameca Instruments, Inc.
Masashi Watanabe, Lehigh University
Jean Audinot, Centre de Recherche Public-Gabriel Lippmann, Luxembourg
Dominique Drouin, University of Sherbrooke, Canada
Colin MacRae, CSIRO Materials, Australia
Adam Hitchcock, McMaster University, Canada
Gerald Kothleitner, TU Graz, Austria
Quantification from the micron to sub-nanometer length scale is a critical part of many studies of materials-both biological and physical in nature. This session will explore current limitations and advances in all aspects of quantitative microanalysis with an emphasis on pushing detection limits and correcting for artifacts over length scales, which include traditional near-surface micro-scale analyses down to atomic-resolution.

A15: In-situ Experiments in Liquids and Gases Using Electron-Optical Instruments
Blythe Clark, Konrad Rykaczewski, Eric A. Stach

Invited Speakers:
Debbie Stokes, FEI Company
Raymond Unocic, Oak Ridge National Laboratory
Seiji Takeda, Osaka University, Japan
James Evans, University of California — Davis
Henny Zandbergen, Delft University of Technology, Netherlands
Agnes Bogner, INSA Lyon, France
Joseph Grogan, University of Pennsylvania
Kate Klein, Zeiss/NIST
Recent advances in microscope and sample holder designs have opened new avenues for in-situ microscopy in liquid and gaseous environments. This symposium will focus on the latest advances in imaging of materials in the presence of liquids and gases in scanning, transmission and scanning transmission electron microscopes. Application areas are expected to include catalysis, oxidation, embrittlement, corrosion, electrochemistry, nanoparticle nucleation and growth, and biological processes and interactions. Invited speakers will be 'going beyond imaging', by emphasizing quantification of data and placing the results from in-situ experimentation into the broader framework of their respective scientific areas of emphasis.

A16: You Never Stop Paying for a Car — The Challenge of Instrument Maintenance in an Era of Shrinking Budgets
Thomas Williams

Invited Speakers:
Debra Sherman, Purdue University
Yagiao Wu, Boise State University
Jeffery Bolin, Purdue University
Instrument maintenance is a constant and rising expense for Core Analytical Facilities. We all depend on outside vendors for service and maintenance. Choices include: demand service, service contracts, and the third-party facilitated maintenance agreements. The goal of the Symposium is to spur discussion of options, best practices, and how to pay the bill. Included in the Symposium: presentations from Vendors, Facility Directors, University Administrators, and Federal Agencies, followed by an open panel discussion. Contributions are invited for a follow-on Poster Session. Without maintenance, instruments go down and fail the users they are there to serve.

29 Jul - 2 Aug 2012

United States of America
meeting website