Small GTPases at Different Scales: Proteins, Membranes, Cells

We are pleased to announce the Cold Spring Harbor Asia conference on Small GTPases at Different Scales: Proteins, Membranes, Cells which will be held at the Suzhou Dushu Lake Conference Center in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday September 24, and will conclude after lunch on Friday September 28, 2012.

This conference is similar in design to the famous Cold Spring Harbor meetings series, a program now in its 76th year. The conference will include eight oral sessions and one poster session. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

Major Topics:
1. Biomolecular simulations and model systems for GTP hydrolysis
2. Molecular mechanism of GTP hydrolysis by small GTPases and their associated GAPs
3. Posttranslational modifications of small GTPases
4. Interactions of small GTPases with membranes
5. Protein-Protein interactions of small GTPases in vitro
6. Dynamics and Trafficking of small GTPases in vivo
7. Lessons from other GTPases for small GTPases
8. Small GTPases in disease and drugs for small GTPases

+ show speakers and program
Invited Speakers:
Klaus Aktories, University of Freiburg, GERMANY
Abstract title: Modification of small GTPases by bacterial protein toxins
Philippe Bastiaens, Max Planck Institute, GERMANY
Abstract title: TBA
Xiao-Wei Chen, University of Michigan, USA
Abstract title: Small GTPase in Metabolic Regulation
Channing Der, University of North Carolina at Chapel Hill, USA
Abstract title: TBA
Jianping Ding, Shanghai Institutes for Biological Sciences,CAS, China
Abstract title: TBA
Mitsunori Fukuda, Tohoku University, Graduate School fo Life Sciences, Japan
Abstract title: The Rab family small GTPases regulate membrane trafficking in melanocytes
Klaus Gerwert, Ruhr-University Bochum, Germany
Abstract title: TBA
Roger Goody, Max Planck Institute, GERMANY
Abstract title: TBA
Alemayehu Gorfe, University of Texas Medical School - Houston, USA
Abstract title: Computational studies of Ras dynamics, membrane binding and assembly
Andrew Goryachev, University of Edinburgh, Center for Systems Biology, United Kingdom
Abstract title: TBA
John Hancock, University of Texas, USA
Abstract title: TBA
Klaus Hahn, University of North Carolina at Chapel Hill School of Medicine, USA
Abstract title: TBA
Christian Herrmann, Ruhr-University Bochum, GERMANY
Abstract title: TBA
Hans Robert Kalbitzer, University of Regensburg, GERMANY
Abstract title: Regulating the activity of small GTPases by small molecules
Yoel Kloog, Tel Aviv University ISRAEL
Abstract title: Ras chaperons for cancer therapy: from concepts to human trials
Toshimasa Ishizaki, Kyoto University, JAPAN
Abstract title: TBA
David Lambright, University of Massachusetts Medical School, USA
Abstract title: TBA
Fang-Jen Lee, National Taiwan University, TAIWAN
Abstract title: TBA
Zhenge Luo, Shanghai Institute of Neuroscience, SIBS, CAS, CHINA
Abstract title: TBA
Edward Manser, Institute of Medical Biology, SINGAPORE
Abstract title: TBA
Didier Marguet, INSERM-CNRS de Marseille-Luminy, FRANCE
Abstract title: Spot variable Fluorescence Correlation Spectroscopy reveals fast scouting of K-Ras at the plasma membrane of living cells
Shuh Narumiya, Kyoto University, JAPAN
Abstract title: TBA
Alexander Nemukhin, M.V.Lomonosov Moscow State University, RUSSIAN
Abstract title: Modeling Chemical steps of enzymatic hydrolysis of GTP
Mark Philips, New York University Cancer Insitute, USA
Abstract title: Ras Trafficking and Signaling
Xiaocheng Wang, National Institute of Biological Sciences, CHINA
Abstract title: TBA
Arieh Warshel, University of Southern California, USA
Abstract title: TBA
Michael White, UT Southwestern Medical Center, USA
Abstract title: TBA
Roland Winter, TU Dortmund, GERMANY
Abstract title: Biophysical Characterization of Ras Protein – Membrane Interactions: Partitioning, Clustering, Lipid Sorting, and Conformational Selection
Yanhui Xu, Fudan University, China
Abstract title: structural insight into the Rag GTPase mediated mTOR Complex 1
Xuewu Zhang, University of Texas Southwestern Medical Center, USA
Abstract title: TBA

24 Sep - 26 Sep 2012
Suzhou Dushu Lake
meeting website