Coinfections 2012

This seminar will highlight recent advances in our understanding of polymicrobial infections, synergies between microbes and relevant aspects of symbiosis.

Ten scientists at the international forefront will give presentations and contribute to the discussions. Also, there will be posters presented by meeting participants. The presentations will cover the entire field from molecules to medicine.

Simultaneous infection of a host by multiple and synergistic pathogens, incremental infections arising by initial infection followed by superinfection and simultaneous coinfection of a single cell occur where one otherwise minor organism unleashes the full pathogenic potential of an established pathogen. When pathogens enforce each other synergistically, disease transmission and progression are enhanced, in syndemism. One prime example of such a globally common coinfection to be highlighted at the meeting involves both tuberculosis and HIV, where one is exacerbating the other in the pandemic.

Coinfections arise with representatives of all classes of microbes, bacteria, viruses, yeast/fungi and parasites as well as combinations of these. Coinfections can also affect each other negatively in microbial interference where one bacterial species suppresses the virulence or colonization of the bacteria, alleviating the pathogenic pressure. One example of the latter is when Pseudomonas aeruginos suppresses pathogenic Staphylococcus aureus colony formation.

The global prevalence of coinfections is commonplace, but the impact of co-infections is greatly underestimated and the actual numbers are currently non-available. We will therefore also elucidate some of the societal impact of coinfections and disease and discuss controversies in regard to pathogenesis, diagnostics and treatment. The multifaceted approach to the emerging field of coinfections makes this conference a “must” for students and researchers in the infection biology sciences. #
+ show speakers and program
Albert Osterhaus, The Netherlands
Topic: Emerging virus infections in a changing world

Søren Molin, Denmark
Topic: Impact of biofilms in Coinfections

Nicolas Fasel, Switzerland
Topic: Leishmania RNA virus and Leishmania

Achim Hoerauf, Germany
Topic: Onchocerca volvulus and the Wolbachia endosymbiont unleashes the immune response eliciting clinical onchocerchiasis

Birgitta Henriques-Normark, Sweden
Topic: Mixed lower respiratory tract infections

Robert J. Wilkinson, United Kingdom
Topic: HIV-1 and the immune response to tuberculosis

Jon McCullers, United States of America
Topic: Influenza and bacterial superinfection

Linda Wammes, The Netherlands
Topic: Immunological consequences of helminth-malaria co-infections

Julie Pfeiffer, United States of America
Topic: How gut bacteria enhance enteric virus infectivity

Stephen Cummings, United Kingdom
Topic: Diversity and activity of free-living nitrogen-fixing bacteria and total bacteria in soils

7 Jun - 8 Jun 2012
meeting website